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Science & technology

Prelims · Science & technology · 30 questions

Biotechnology & genetics

Every UPSC Prelims question on this topic, 2016–2026, newest first. Tap an option to check yourself; the answer and explanation open below it.

Biotechnology & genetics questions per year: 2016: 1, 2017: 2, 2018: 1, 2019: 3, 2020: 2, 2021: 3, 2022: 1, 2023: 2, 2024: 0, 2025: 2, 2026: 2 Asked in 10 of 11 years · most in 2021 (3)

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UPSC syllabus: “General Science.” Sub-topics in the detailed syllabus →

‘वोलबैचिया पद्धति’ का कभी-कभी निम्नलिखित में से किस एक के संदर्भ में उल्लेख होता है?

Read this question in English

'Wolbachia method' is sometimes talked about with reference to which one of the following?

(a) Controlling the viral diseases spread by mosquitoes · (b) Converting crop residues into packing material · (c) Producing biodegradable plastics · (d) Producing biochar from thermochemical conversion of biomass

उत्तर और व्याख्या · explanation in English

Answer: (a) मच्छरों से होने वाले विषाणु रोगों के प्रसार को नियंत्रित करना

The Wolbachia method is used to control viral diseases spread by mosquitoes, mainly dengue. Wolbachia is a bacterium that lives naturally in many insects; when it is introduced into Aedes aegypti mosquitoes, they transmit dengue virus much less.

  • ✓ (a) Wolbachia has been transferred into Aedes aegypti mosquitoes and reduces their transmission of dengue virus. WHO's Vector Control Advisory Group has assessed the approach and confirmed its public health value for dengue control.
  • ✗ (b) Turning crop residue into packing material is a materials process and has nothing to do with a bacterium living inside insects.
  • ✗ (d) Biochar comes from heating biomass in a thermochemical process such as pyrolysis. It is not a mosquito-control method.

Remember · Wolbachia is an insect-dwelling bacterium. Released in Aedes aegypti mosquitoes, it cuts dengue transmission, so it is a mosquito-borne disease control method.

Sources

Question and answer: UPSC's official GS Paper I (2023, Series A) — paper ↗ · answer key ↗. Explanation: Minimalist IAS, checked 30 Sept 2026 (how we verify). Permalink ·

‘एरियल मेटाजिनोमिक्स’ निम्नलिखित में से किस एक स्थिति को सबसे सही निर्दिष्ट करता है?

Read this question in English

'Aerial metagenomics' best refers to which one of the following situations?

(a) Collecting DNA samples from air in a habitat at one go · (b) Understanding the genetic makeup of avian species of a habitat · (c) Using air-borne devices to collect blood samples from moving animals · (d) Sending drones to inaccessible areas to collect plant and animal samples from land surfaces and water bodies

उत्तर और व्याख्या · explanation in English

Answer: (a) किसी पर्यावास में वायु से डी॰ एन॰ ए॰ प्रतिदर्शों को एक बार में एकत्र करना

Aerial metagenomics means collecting DNA from the air in a habitat and sequencing it all together to see which organisms are present. Metagenomics studies the combined genetic material of many organisms in one bulk sample, and here the sample is air.

  • ✓ (a) Air carries tiny particles (bioaerosols) shed by microbes, plants and animals. Sampling that air and sequencing the DNA in it at one go reveals the species around, without catching or disturbing any animal.
  • ✗ (b) This describes genetic study of birds only. Metagenomics covers a whole mixed community of organisms in one sample, not one group such as avian species.
  • ✗ (d) Drones collecting physical plant and animal samples from land and water are a sampling method, not a study of DNA collected from air.

Remember · Metagenomics reads the DNA of a whole community from one bulk sample. In aerial metagenomics that sample is air, giving a snapshot of the species around.

Sources

Question and answer: UPSC's official GS Paper I (2023, Series A) — paper ↗ · answer key ↗. Explanation: Minimalist IAS, checked 1 Oct 2026 (how we verify). Permalink ·

‘माइक्रोसैटेलाइट डी॰ एन॰ ए॰’ निम्नलिखित में से किस एक मामले में प्रयोग किया जाता है?

Read this question in English

'Microsatellite DNA' is used in the case of which one of the following?

(a) Studying the evolutionary relationships among various species of fauna · (b) Stimulating 'stem cells' to transform into diverse functional tissues · (c) Promoting clonal propagation of horticultural plants · (d) Assessing the efficacy of drugs by conducting series of drug trials in a population

उत्तर और व्याख्या · explanation in English

Answer: (a) प्राणिजात की विभिन्न जातियों के बीच विकासपरक संबंधों का अध्ययन करना

Microsatellite DNA is used to study genetic variation between individuals and populations, which is why it helps in tracing evolutionary relationships among species. Microsatellites are short DNA stretches repeated many times, and the number of repeats varies from one organism to another.

  • ✓ (a) Because repeat numbers in microsatellites differ so much between individuals and populations, they work as genetic markers. Comparing them shows how closely related organisms or populations are.
  • ✗ (b) Turning stem cells into different tissues is done with growth signals and culture conditions. It does not use microsatellite DNA.
  • ✗ (d) Drug trials in a population test how well a medicine works. Microsatellites do not assess drug efficacy.

Remember · Microsatellites are short repeated DNA stretches whose repeat number varies between individuals. They serve as genetic markers, for DNA fingerprinting and for studying relationships and diversity.

📘 Read it in NCERT: Class 12 Biology, Ch 5 (practise this chapter)

Sources

Question and answer: UPSC's official GS Paper I (2023, Series A) — paper ↗ · answer key ↗. Explanation: Minimalist IAS, checked 30 Sept 2026 (how we verify). Permalink ·

The Syllabus X-Ray of this topic

1 of its 5 sub-topics is Core

1 Core · 1 High · 2 Steady · 1 Rare

  • Core #11DNA, genes & genome editing · 11 questions
  • HighStem cells, cloning & new therapies · 3 questions

The X-Ray ranks all 928 sub-topics of the UPSC syllabus by what UPSC has asked since 2016. The 60 Prelims Core sub-topics are behind 51% of Prelims questions.

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The same topic in Mains

Read it in NCERT