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Prelims 2022 paper

UPSC CSE Prelims 2022 · Question 39 · Human body, health & diseases

In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following…

Prelims 2022 · Q39

Human body, health & diseases Medium

In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements:

  1. 1.The Serum Institute of India produced COVID-19 vaccine named Covishield using mRNA platform.
  2. 2.Sputnik V vaccine is manufactured using vector based platform.
  3. 3.COVAXIN is an inactivated pathogen based vaccine.

Which of the statements given above are correct?

Answer & explanation

Answer: (b) 2 and 3 only

Statements 2 and 3 are correct. Sputnik V is a vector vaccine and COVAXIN is a whole-virus inactivated vaccine. Statement 1 is wrong because Covishield, made by the Serum Institute of India, is a viral-vector vaccine (adenovirus carrier), not an mRNA vaccine.

  • ✗ 1. Covishield is the Oxford-AstraZeneca vaccine produced in India by the Serum Institute. It uses a weakened chimpanzee adenovirus as a carrier, so it is a viral-vector vaccine. No mRNA is involved.
  • ✓ 2. Sputnik V (Gam-COVID-Vac) from Russia's Gamaleya Institute is a combined vector vaccine given in two components.
  • ✓ 3. COVAXIN by Bharat Biotech, developed with ICMR-NIV, uses a whole-virion inactivated Vero-cell platform: dead virus that cannot infect but still trains the immune system.

Remember · Covishield and Sputnik V: viral-vector vaccines. COVAXIN: inactivated whole virus. ZyCoV-D: DNA. mRNA is the Pfizer and Moderna type.

Sources

Question and answer: UPSC's official GS Paper I (2022, Series A) — paper ↗ · answer key ↗. Explanation: Minimalist IAS, checked 30 Sept 2026 (how we verify). ·

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