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UPSC CSE Prelims 2021 · Question 73 · Human body, health & diseases

The term ‘ACE2’ is talked about in the context of

Prelims 2021 · Q73

Human body, health & diseases Easy

The term ‘ACE2’ is talked about in the context of

Answer & explanation

Answer: (d) spread of viral diseases

ACE2, short for angiotensin-converting enzyme 2, sits on the outer surface of human cells, and the spike of SARS-CoV-2 (the virus behind COVID-19) latches onto it to get inside. So it was discussed in the context of how a viral disease spreads.

  • ✓ (d) The spike protein of SARS-CoV-2 binds to ACE2 on host cells, which lets the virus enter them. The earlier SARS coronavirus used the same receptor.
  • ✗ (a) ACE2 is a human protein, not a gene introduced into genetically modified plants.
  • ✗ (b) India's own satellite navigation system is NavIC; ACE2 has nothing to do with navigation or radio collars.

Remember · ACE2 is the human cell-surface receptor that SARS-CoV-2 (and SARS-CoV) binds to for entry into cells.

Sources

Question and answer: UPSC's official GS Paper I (2021, Series A) — paper ↗ · answer key ↗. Explanation: Minimalist IAS, checked 30 Sept 2026 (how we verify). ·

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